Balekuduru A and Sahu MK. Expert opinion on the habit forming properties of laxatives in patients with constipation [version 1; peer review: awaiting peer review]. F1000Research 2022, 11:803.
Schiller, L.R., The therapy of constipation. Alimentary Pharmacology & Therapeutics, 2001; 15: 749-763. https://doi.org/10.1046/j.1365-2036.2001.00982.x.
L Kosar MSc, B Schuster P. Management of constipation. RX Files Aug 2013. Available from: https://www.mindmeister.com/generic_files/get_file/6624119?filetype=attachment_file |Based on individual properties of milk of magnesia and liquid paraffin.
Udani JK, et al. Effects of kivia powder on Gut health in patients with occasional constipation: a randomized, double-blind, placebo-controlled study. Nutrition Journal 2013,12:78.
SMSRC MAT FEB 2020. Cremaffin is No.1 prescribed laxative brand in Milk of Magnesia laxatives.
Kinnunen O. Constipation in elderly longstay patients: Its treatment by magnesium hydroxide and bulk laxatives. Annals of Clinical Research 1987;19:321-23.
Sharif F, Crushell E, O’Driscoll K et. al. Liquid paraffin: a reappraisal of its role in the treatment of constipation. Arch Dis Child 2001;85:121-124.
Portalatin M, Winstead N. Medical management of constipation. Clin Colon Rectal Surg. 2012;25(1):12—-19.
Bharucha AE et al. American Gastroenterological Association technical review on constipation. Gastroenterology. 2013;144(1):218-238.
Connolly P, et al. Curr Med Res Opin 1974;2:620- 625. Rowann-Legg A. Paediatr Child Health. 2011;16(10):661-665.Sharif Ft al. Arch Dis Child. 2001;85:121-124. Cremaffin contains Milk of Magnesia, an osmotic laxative and Liquid Paraffin, a lubricant laxative, which are known to be non-habit forming. The “non-habit forming” claim is not based on any direct studies relating to Milk of Magnesia and Liquid Paraffin.
Cremaffin presenting information. Abbott India Limited.
Data on File, Cremaffin Packshot.
MA Kamm et al. Oral Bisacodyl Is Effective and Well-Tolerated in Patients With Chronic Constipation. Clinical Gastroenterology and Hepatology 2011;9:577- 583.
Jauch R et al. Bis-(p-hydroxyphenyl)-pyridyl-2-methane: The Common laxative principle of Biscodyl and sodium picosulfate. Arzneimittelforschung. 1975;25(11):1796-1800.
Lembo A, et al. Chronic Constipation. N Engl J Med 2003;349:1360-8.
Lembo A, et al. Chronic Constipation. N Engl J Med 200;349:1360-8.
